Epoxide Hydrolases: A Biocatalytic Technology Platform for the Production of Chiral Pharmaceutical Intermediates
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چکیده
Enantiomerically pure epoxides and vicinal diols are key chiral synthons. Epoxide hydrolases (EHs) offer access to both chiral epoxides and vicinal diols and the development of a cost-effective technology based on EHs offers a compelling ‘green’ alternative to current asymmetric chemical technologies. This article describes the assumptions, innovations and developments that have allowed Oxyrane to progress EH technology into a versatile proprietary biocatalytic platform. The technology has now been validated for multiple applications at relevant commercial scale for existing as well as new and innovative products.
منابع مشابه
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تاریخ انتشار 2007